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Analysis of the Current Opportunities within the Development of Polymorphic Screening Methods as we Search for New, Stable Polymorphs and the Hurdles Faced Along the Way
Senior Research Advisor
Eli Lilly and Company
Selection of an optimal crystalline form of an active pharmaceutical ingredient plays a critical role in the different stages of drug development impacting bioavailability, solubility, stability, and other physical properties of a drug candidate. Identification and evaluation of solid phases of a drug are critical in defining a stable platform for robust processing from bench scale to plant scale manufacturing and formulation.
Molecular and Materials Characterisation
Associate Director of Solid State Characterisation and Development
A: Continuous Crystallisation
Novartis-MIT Centre for Continuous Manufacturing
B: Speeding Up Scale Up From Lab to Pilot
Professor of Process Systems Engineering
University of Loughborough
C: Control of The Crystallisation Process
D: Assessing Stability of Polymorphs
Research and Application Scientist
Cambridge Crystallographic Data Centre
Quality by Design is becoming increasingly important in the Pharmaceutical Industry with more focus being placed on control and understanding of polymorphism. Solid Form Informatics makes use of the vast amount of solid state interaction data in the Cambridge Structure Database to provide predictive analytics in the area of substance development and risk assessment. This presentation aims to show how these methods can provide the following:
European Patent Office
Principal Scientist, Crystallisation
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